Molecular formula is C16H13NO2•HCl
The molecular weight of tramadol hydrochloride is 299.8. Tramadol hydrochloride is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9.41. The noctanol/water log partition coefficient (logP) is 1.35 at pH7. Tramadol hydrochloride tablets, for oral administration contain 50 mg of tramadol hydrochloride. In addition, each tablet contains the following inactive ingredients: pregelatinized starch, lactose anhydrous, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, titanium dioxide.
The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
How to Use:
Follow the directions for using Esgic Plus provided by your doctor. STORE Esgic Plus at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF Esgic Plus and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
SIDE EFFECTS, that may go away during treatment, include drowsiness, dizziness, lightheadedness, or nausea. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
DO NOT EXCEED THE RECOMMENDED DOSE or take Esgic Plus for longer than prescribed without checking with your doctor. Exceeding the recommended dose or taking Esgic Plus for longer than prescribed may be habit-forming. AVOID ALCOHOL while you are using Esgic Plus. Esgic Plus will add to the effects of alcohol and other depressants. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to Esgic Plus. Using Esgic Plus alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. Esgic Plus CONTAINS ACETAMINOPHEN. Do not take additional acetaminophen for pain or fever without checking with your doctor or pharmacist. Ask your pharmacist if you have questions about which medicines contain acetaminophen. Acetaminophen may cause liver damage. If you drink alcohol on a daily basis, do not take Esgic Plus without first discussing it with your doctor. Alcohol use combined with acetaminophen may increase your risk for liver damage. Pain medications work best if they are used as the first signs of pain (or first signs of migraine) occur. If you wait until the pain has significantly worsened, the pain medicine may not work as well. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN TAKING BIRTH CONTROL PILLS: Esgic Plus may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are taking Esgic Plus. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Esgic Plus during pregnancy. Esgic Plus IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking Esgic Plus.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other.
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include vomiting, excessive sweating, dark urine, stomach pain, extreme fatigue, unusual drowsiness or dizziness, lack of feeling alert, slow or shallow breathing, cold or clammy skin, and loss of consciousness.
IF YOUR HEADACHE SYMPTOMS do not improve or if they become worse, contact your doctor. DO NOT SHARE Esgic Plus with others for whom it was not prescribed. DO NOT USE Esgic Plus for other health conditions. KEEP Esgic Plus out of the reach of children. IF USING Esgic Plus FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.